Mission

The TAGC functional genomics staff conducts original cognitive research involving in physiological and pathological situations, based on transcriptional and post-translational analyses, as well as a Chip-on-chip approach. The tools developed are then transferred to the transcriptomics platform.

Tools in development

Some of our Tools ChIP-on-chip approach In vivo electroporation development

Projects

The recent improvements of sequencing technologies, and in particular the publication of the initial version of the human genome sequence together with the large-scale sequencing of transcribed sequences, have opened the field of large-scale functional approaches of biological systems: functional genomics. Transcriptional analysis of thymic development Analysis of the transcriptional regulation of T lymphocyte activation Analysis of post-translational modifications Analysis of the transcription regulatory network in breast cancers Sepsis project

Valorisation

Main lab patents : PCT/IB01/02811. INSERM 01209 PCT/FR04/03084 : valorised by Ipsogen Startups :

Team

The FunctionalGenomics team members.

Collaborations

Human MicroArray:
GALDERMA	Industry	Psoreasis	Sophia antipolis
Pascale Cohen	CNRS UMR5535	Chimio Resistancy	Montpellier
Mélanie Nugoli	CNRS UMR5535	Genome and Cancer	Montpellier
François Berger	INSERM U318	Glioblastoma	Grenoble
Bernadette Barbarat	INSERM U119	Tumours Immunology	Marseille
Elisabeth Devilard	IPC	Hodgkin Disease	Marseille
Cécile Tonnelle	IPC	B Lymphoma	Marseille
Jean-Louis Formento	Ctre Lacassagne	Chimio Sensitivity	Nice
Charles Theillet	EMI 0229	Breast Cancer	Marseille
Daniel Birnbaum	INSERM U119	Breast Cancer	Marseille
Francine Anfosso	INSERM EMI0019	Autoimmunity	Marseille
C Schiff	INSERM U136	Leukaemia	Marseille
Christophe Chevillard	INSERM U399	Bilharziose/Paludism	Marseille
Stéphane Minvielle	INSERM U463	Myeloma	Nantes
Florence Magrangeas	INSERM U463	Myeloma	Nantes
Olivier Delattre	Institut Curie	Medulloblastoma	Paris
JL Berge-Lefranc	EA 1784	Toxicology	Marseille
Baris O ,Malthiery Y	INSERM EMI-U 00018	Oncocythome	Angers
Catherine Thieblemond	Hôpital Lyon sud	Lymphoma	Lyon
Patricia Paris	IMTSSA	Dengue	Marseille
Brigitte Autran	INSERM U543	HIV	Paris
Ivan Hirch	INSERM U372	HIV	Marseille
Behazine Combadiere	INSERM U541	HIV	Paris
.
Mus musculus MicroArray:
Vassilios Aidini		Autoimmunity	Greece
Geraldo Passos		T Cell Differenciation	Brasil
Michel Samson	INSERM U435	Testis	Rennes
Pascal Rihet	EA864, IFR 48	Paludism	Marseille
Nathalie Auphan	INSERM U 136	T Cell Differenciation	Marseille
Nadia Daman	CNRS UMR 6156	SNC Regionalisation	Marseille
Franck Galland	INSERM 136	Oxydative Response	Marseille